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Sunday, July 12, 2020 | History

1 edition of Biopersistence of respirable synthetic fibers and minerals found in the catalog.

Biopersistence of respirable synthetic fibers and minerals

Biopersistence of respirable synthetic fibers and minerals

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  • 36 Currently reading

Published by National Institutes of Health, National Institute of Environmental Health Sciences in [Research Triangle Park, NC] .
Written in English

    Subjects:
  • Textile fibers, Synthetic -- Toxicology -- Congresses,
  • Fibers -- Toxicology -- Congresses,
  • Minerals -- Toxicology -- Congresses,
  • Persistent pollutants -- Toxicology -- Congresses,
  • Air -- Pollution -- Toxicology -- Congresses,
  • Lungs -- Diseases -- Congresses

  • Edition Notes

    SeriesEnvironmental health perspectives -- v. 102, suppl. 5, DHHS publication -- no. (NIH) 94-218, NIH publication -- no. NIH 94-218, NIH publication -- no. 94-218
    ContributionsNational Institute of Environmental Health Sciences, INSERM-IARC-CNRS Workshop on Biopersistence of Respirable Synthetic Fibers and Minerals (1992 : Lyon, France)
    The Physical Object
    Pagination292 p. :
    Number of Pages292
    ID Numbers
    Open LibraryOL14959264M

    Biopersistence of Respirable Synthetic Fibers and Minerals, held September in Lyon, France. Address correspondence to De Vuyst, Hopital Erasme, Universite Libre de Bruxelles, Route de Lennik , Bruxelles, Belgium. Telephone 32 exposed to cobalt dust arising from dia-mond-cobalt polishing discs, and died. (). BIOPERSISTENCE OF SYNTHETIC MINERAL FIBERS AS A PREDICTOR OF CHRONIC INHALATION TOXICITY IN RATS. Inhalation Toxicology: Vol. 13, No. 10, pp.

    Biopersistence of Inhaled Organic and Inorganic Fibers in the Lungs of Rats Article (PDF Available) in Environmental Health Perspectives Suppl 5(Suppl 5) October with 46 Reads. Biopersistence of Respirable Synthetic Fibers and Minerals: Point of View of the Chest Physician.

    Biopersistence of fibers and minerals in human respiratory tissues is an important aspect of the toxicity of these agents. However, few data are available from human studies. Although a number of studies have measured the lung burden of asbestos and other minerals in exposed humans. A Review of Fiber Biopersistence. as. a Potential Mechanism of Asbestos Tumorigenicity. David Bernstein. Thomas Hesterberg. Ken Donaldson. Gunther Oberdörster. Abstract: It is well accepted that the dose, dimensions, durability of respirable fibers in the lung, and in some cases the surface characteristics of the fibers, are the critical determinants of their potential adverse health effects.


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Biopersistence of respirable synthetic fibers and minerals Download PDF EPUB FB2

Biopersistence of fibers and minerals in human respiratory tissues is an important aspect of the toxicity of these agents. However, few data are available from human studies. Although a number of studies have measured the lung burden of asbestos and other minerals in exposed humans, few presented information relevant to biopersistence of these Cited by: 1.

Get this from a library. Biopersistence of respirable synthetic fibers and minerals. [National Institute of Environmental Health Sciences.;]. Biopersistence of respirable synthetic fibers and minerals: point of view of the chest physician.

P De Vuyst Hôpital Erasme, Université Libre de Bruxelles, by: 5. Introduction: INSERM-IARC-CNRS workshop on biopersistence of respirable synthetic fibers and minerals.

J Bignon, R Saracci, and J C Touray INSERM UnitéCHU Henri Mondor, Créteil, by: The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials.

The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal by:   Fiber biopersistence as a major mechanism of fiber-induced pathogenicity was investigated.

The lung biopersistence of 5 synthetic vitreous fibers (SVFs) and amosite asbestos was evaluated using the rat inhalation model.

In contrast to several previous studies, this study examined fibers that dissolve relatively slowlyin vitroat pH Fisher.

CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials.

The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model. While acellular and in vitro systems are important for initial. The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials.

The biopersistence of respirable synthetic fibers and minerals in mancan bemostclosely evaluated in an animal model. Whileacellular and in vitro systemsare important. Fibrous glass dust, Mineral wool fiber (synthetic vitreous fibers) 5 mg/m 3 (total) 3 f/cm 3 (fibers ≤ µm in diameter & ≥ 10μm in length) State of California's Established PEL - TWA: Fibrous glass (as Glass) 1 f/cc (1) Mineral wool fiber (as Particulates not otherwise regulated, or nuisance particulates) 5 mg/m 3 (total dust).

For synthetic mineral fibers, the biopersistence of the fibers longer than 20 μm was found to be highly correlated with pathological response in chronic inhalation studies, and with tumorigenic potential in chronic intraperitoneal injection studies.

The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials. The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model.

The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials. The biopersistence of respirable synthetic fibers and minerals in.

An experimental approach to the evaluation of the biopersistence of respirable synthetic fibers and minerals. Bernstein DM, Mast R, Anderson R, Hesterberg TW, Musselman R, Kamstrup O, Hadley J.

Environ Health Perspect, Suppl01 Oct   In the case of synthetic vitreous fibers, biopersistence fibers were classified as highly hazardous, while non-biopersistence fibers were classified as low hazard. para-Aramid has a medium level of hazard as it is similar in the size of fibers that are known to be carcinogenic and may be exposed as respirable fibers.

Some of them, i.e. asbestos, several asbestiform minerals (e.g., asbestiform winchite and asbestiform fluoredenite), and certain synthetic vitreous fibers (e.g., Gunter et al., ; Utell and Maxim, ) are well known for their adverse health effects when respired in high doses as in case of professional exposure (e.g., Lippmann, ; Park.

Biopersistence. Refractory. Ceramic. Fiber. were found 5 d after inhalation exposure to a synthetic vitreous fiber (refractory ceramic fiber) aerosol ().

that all respirable. An experimental approach to the evaluation of the biopersistence of respirable synthetic fibers and minerals Environ. Health Perspect., (Suppl. 5) (), pp. The biopersistence of fibers and minerals in the respiratory tract is an important parameter in the toxicity of those materials.

The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model. While acellular and in vitro systems are important for initial evaluation of solubility and.

Biopersistence of respirable synthetic fibers and minerals: the point of view of the epidemiologist Boffetta, Paolo // Environmental Health Perspectives Supplements; Supplement 5, Vol.p No abstract available. The biopersistence of respirable synthetic fibers and minerals in man can be most closely evaluated in an animal model.

While acellular and in vitro systems are important for initial evaluation of solubility and durability, they cannot simulate the dynamics of inhalation. BibTeX @MISC{Vuyst_biopersistenceof, author = {Paul De Vuyst}, title = {Biopersistence of Respirable Synthetic Fibers and Minerals: Point of View of the Chest Physician}, year = {}}.

Hyg. 31, McClellan, R. 0. and Hesterberg, T. W. () Role of biopersistence in the pathogenicity of man-made fibers and methods for evaluating biopersistence—a summary of two round-table discussions. In Biopersistence of Respirable Synthetic Fibres and Minerals.

Environ. Hith Perspect.Suppl. 5. The Occupational Safety and Health Administration (OSHA) has set a limit of 5 milligrams of synthetic vitreous fibers as inert or nuisance dust per cubic meter (5 mg/m 3) of air for the respirable fraction and 15 mg/m 3 for total dust. The voluntary limit for fiberglass and mineral wool is 1 fiber per cubic centimeter.